I kind of wonder about that reasoning, though. I mean, no it's not trivial if you imagine having to foot the bill for it yourself, but proportional to the kind of money Twitter is dealing with, it's, well, still just 1% of a JS file.
But I don't think we need to think of it in terms of Twitter's scale at all. The point is that saving 1% for basically free, is saving 1% for basically free, and that's worthwhile no matter how big you are. On its own, it's a drop in the bucket, but the cumulative effect of many small low-opportunity-cost savings is a significant low-opportunity-cost saving.